Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts

Tumor collagen characteristics influence tumor malignancy, invasion, and metastasis. This study investigates the effects of trastuzumab (Tz) on the collagen of Tz-responsive (BT474) and Tz-resistant (HR6) breast cancer xenografts. Collagen content was assessed by in vivo second harmonic generation (...

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Dades bibliogràfiques
Publicat a:J Biomed Opt
Autors principals: Walsh, Alex J., Cook, Rebecca S., Lee, Jae H., Arteaga, Carlos L., Skala, Melissa C.
Format: Artigo
Idioma:Inglês
Publicat: Society of Photo-Optical Instrumentation Engineers 2015
Matèries:
Research Papers: Imaging
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335617/
https://ncbi.nlm.nih.gov/pubmed/25700233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.20.2.026004
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