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In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts

HER2-amplified (HER2 + ) breast cancers are treated with the anti-HER2 monoclonal antibody trastuzumab. Although trastuzumab reduces production of the angiogenic factor VEGF in HER2 + tumors, the acute and sustained effects of trastuzumab on the tumor vasculature are not understood fully, particular...

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Bibliografiske detaljer
Main Authors: McCormack, Devin R., Walsh, Alex J., Sit, Wesley, Arteaga, Carlos L., Chen, Jin, Cook, Rebecca S., Skala, Melissa C.
Format: Artigo
Sprog:Inglês
Udgivet: Optical Society of America 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102362/
https://ncbi.nlm.nih.gov/pubmed/25071962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.5.002247
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