Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell donors and GMP-compliant manufacturing of antiviral T cells

BACKGROUND: The adoptive transfer of allogeneic antiviral T lymphocytes derived from seropositive donors can safely and effectively reduce or prevent the clinical manifestation of viral infections or reactivations in immunocompromised recipients after hematopoietic stem cell (HSCT) or solid organ tr...

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Detalles Bibliográficos
Publicado en:J Transl Med
Main Authors: Tischer, Sabine, Priesner, Christoph, Heuft, Hans-Gert, Goudeva, Lilia, Mende, Wolfgang, Barthold, Marc, Kloeß, Stephan, Arseniev, Lubomir, Aleksandrova, Krasimira, Maecker-Kolhoff, Britta, Blasczyk, Rainer, Koehl, Ulrike, Eiz-Vesper, Britta
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335407/
https://ncbi.nlm.nih.gov/pubmed/25510656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0336-5
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