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Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell donors and GMP-compliant manufacturing of antiviral T cells

BACKGROUND: The adoptive transfer of allogeneic antiviral T lymphocytes derived from seropositive donors can safely and effectively reduce or prevent the clinical manifestation of viral infections or reactivations in immunocompromised recipients after hematopoietic stem cell (HSCT) or solid organ tr...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Tischer, Sabine, Priesner, Christoph, Heuft, Hans-Gert, Goudeva, Lilia, Mende, Wolfgang, Barthold, Marc, Kloeß, Stephan, Arseniev, Lubomir, Aleksandrova, Krasimira, Maecker-Kolhoff, Britta, Blasczyk, Rainer, Koehl, Ulrike, Eiz-Vesper, Britta
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335407/
https://ncbi.nlm.nih.gov/pubmed/25510656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0336-5
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