Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell donors and GMP-compliant manufacturing of antiviral T cells

BACKGROUND: The adoptive transfer of allogeneic antiviral T lymphocytes derived from seropositive donors can safely and effectively reduce or prevent the clinical manifestation of viral infections or reactivations in immunocompromised recipients after hematopoietic stem cell (HSCT) or solid organ tr...

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Bibliographic Details
Published in:J Transl Med
Main Authors: Tischer, Sabine, Priesner, Christoph, Heuft, Hans-Gert, Goudeva, Lilia, Mende, Wolfgang, Barthold, Marc, Kloeß, Stephan, Arseniev, Lubomir, Aleksandrova, Krasimira, Maecker-Kolhoff, Britta, Blasczyk, Rainer, Koehl, Ulrike, Eiz-Vesper, Britta
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335407/
https://ncbi.nlm.nih.gov/pubmed/25510656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0336-5
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