A Novel Post-translational Modification of Nucleolin, SUMOylation at Lys-294, Mediates Arsenite-induced Cell Death by Regulating gadd45α mRNA Stability

Nucleolin is a ubiquitously expressed protein and participates in many important biological processes, such as cell cycle regulation and ribosomal biogenesis. The activity of nucleolin is regulated by intracellular localization and post-translational modifications, including phosphorylation, methyla...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhang, Dongyun, Liang, Yuguang, Xie, Qipeng, Gao, Guangxun, Wei, Jinlong, Huang, Haishan, Li, Jingxia, Gao, Jimin, Huang, Chuanshu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335216/
https://ncbi.nlm.nih.gov/pubmed/25561743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.598219
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