Disassembly of Lys(11) and Mixed Linkage Polyubiquitin Conjugates Provides Insights into Function of Proteasomal Deubiquitinases Rpn11 and Ubp6

Protein homeostasis is largely dependent on proteolysis by the ubiquitin-proteasome system. Diverse polyubiquitin modifications are reported to target cellular proteins to the proteasome. At the proteasome, deubiquitination is an essential preprocessing event that contributes to degradation efficien...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mansour, Wissam, Nakasone, Mark A., von Delbrück, Maximilian, Yu, Zanlin, Krutauz, Daria, Reis, Noa, Kleifeld, Oded, Sommer, Thomas, Fushman, David, Glickman, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335208/
https://ncbi.nlm.nih.gov/pubmed/25389291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568295
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