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Dimeric Quaternary Structure of Human Laforin
The phosphatase laforin removes phosphate groups from glycogen during biosynthetic activity. Loss-of-function mutations in the gene encoding laforin is the predominant cause of Lafora disease, a fatal form of progressive myoclonic epilepsy. Here, we used hybrid structural methods to determine the mo...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335197/ https://ncbi.nlm.nih.gov/pubmed/25538239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.627406 |
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