FHL1 Reduces Dystrophy in Transgenic Mice Overexpressing FSHD Muscular Dystrophy Region Gene 1 (FRG1)

Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal-dominant disease with no effective treatment. The genetic cause of FSHD is complex and the primary pathogenic insult underlying the muscle disease is unknown. Several disease candidate genes have been proposed including DUX4 and FRG1. Exp...

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Vydáno v:PLoS One
Hlavní autoři: Feeney, Sandra J., McGrath, Meagan J., Sriratana, Absorn, Gehrig, Stefan M., Lynch, Gordon S., D’Arcy, Colleen E., Price, John T., McLean, Catriona A., Tupler, Rossella, Mitchell, Christina A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335040/
https://ncbi.nlm.nih.gov/pubmed/25695429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117665
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