FHL1 Reduces Dystrophy in Transgenic Mice Overexpressing FSHD Muscular Dystrophy Region Gene 1 (FRG1)

Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal-dominant disease with no effective treatment. The genetic cause of FSHD is complex and the primary pathogenic insult underlying the muscle disease is unknown. Several disease candidate genes have been proposed including DUX4 and FRG1. Exp...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Feeney, Sandra J., McGrath, Meagan J., Sriratana, Absorn, Gehrig, Stefan M., Lynch, Gordon S., D’Arcy, Colleen E., Price, John T., McLean, Catriona A., Tupler, Rossella, Mitchell, Christina A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335040/
https://ncbi.nlm.nih.gov/pubmed/25695429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117665
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