Direct Measurement of the pK Values of an Alkaline Bohr Group in Human Hemoglobin
Proton nuclear magnetic resonance spectra of normal and des-(his 146β) human hemoglobin in the aromatic resonance region have been compared at different pH values. From these measurements, a pK value for histidine 146β of 7.1 in carbonmonoxyhemoglobin and 8.0 in deoxyhemoglobin has been found. These...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1973
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4515623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.4.1246 |
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