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Direct Measurement of the pK Values of an Alkaline Bohr Group in Human Hemoglobin

Proton nuclear magnetic resonance spectra of normal and des-(his 146β) human hemoglobin in the aromatic resonance region have been compared at different pH values. From these measurements, a pK value for histidine 146β of 7.1 in carbonmonoxyhemoglobin and 8.0 in deoxyhemoglobin has been found. These...

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Main Authors: Kilmartin, J. V., Breen, J. J., Roberts, G. C. K., Ho, C.
Formato: Artigo
Idioma:Inglês
Publicado: 1973
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC433468/
https://ncbi.nlm.nih.gov/pubmed/4515623
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