Discovery of Transcription Factors and Regulatory Regions Driving In Vivo Tumor Development by ATAC-seq and FAIRE-seq Open Chromatin Profiling

Genomic enhancers regulate spatio-temporal gene expression by recruiting specific combinations of transcription factors (TFs). When TFs are bound to active regulatory regions, they displace canonical nucleosomes, making these regions biochemically detectable as nucleosome-depleted regions or accessi...

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Vydáno v:PLoS Genet
Hlavní autoři: Davie, Kristofer, Jacobs, Jelle, Atkins, Mardelle, Potier, Delphine, Christiaens, Valerie, Halder, Georg, Aerts, Stein
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334524/
https://ncbi.nlm.nih.gov/pubmed/25679813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004994
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