EFFECTIVE, LOW TITER, ANTIBODY PROTECTION AGAINST LOW-DOSE REPEATED MUCOSAL SHIV CHALLENGE IN MACAQUES

Neutralizing antibodies are thought crucial to HIV vaccine protection but a major hurdle is the high antibody concentrations likely required as suggested by studies in animal models(1). However, these studies typically apply a large virus inoculum to ensure infection in control animals in single cha...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Hessell, Ann J., Poignard, Pascal, Hunter, Meredith, Hangartner, Lars, Tehrani, David M., Bleeker, Wim K., Parren, Paul W.H.I., Marx, Preston A., Burton, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334439/
https://ncbi.nlm.nih.gov/pubmed/19525965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1974
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