Elevated In Vivo Levels of a Single Transcription Factor Directly Convert Satellite Glia into Oligodendrocyte-like Cells

Oligodendrocytes are the myelinating glia of the central nervous system and ensure rapid saltatory conduction. Shortage or loss of these cells leads to severe malfunctions as observed in human leukodystrophies and multiple sclerosis, and their replenishment by reprogramming or cell conversion strate...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Weider, Matthias, Wegener, Amélie, Schmitt, Christian, Küspert, Melanie, Hillgärtner, Simone, Bösl, Michael R., Hermans-Borgmeyer, Irm, Nait-Oumesmar, Brahim, Wegner, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334169/
https://ncbi.nlm.nih.gov/pubmed/25680202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005008
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