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Elevated In Vivo Levels of a Single Transcription Factor Directly Convert Satellite Glia into Oligodendrocyte-like Cells

Oligodendrocytes are the myelinating glia of the central nervous system and ensure rapid saltatory conduction. Shortage or loss of these cells leads to severe malfunctions as observed in human leukodystrophies and multiple sclerosis, and their replenishment by reprogramming or cell conversion strate...

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Vydáno v:PLoS Genet
Hlavní autoři: Weider, Matthias, Wegener, Amélie, Schmitt, Christian, Küspert, Melanie, Hillgärtner, Simone, Bösl, Michael R., Hermans-Borgmeyer, Irm, Nait-Oumesmar, Brahim, Wegner, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334169/
https://ncbi.nlm.nih.gov/pubmed/25680202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005008
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