Elevated In Vivo Levels of a Single Transcription Factor Directly Convert Satellite Glia into Oligodendrocyte-like Cells

Oligodendrocytes are the myelinating glia of the central nervous system and ensure rapid saltatory conduction. Shortage or loss of these cells leads to severe malfunctions as observed in human leukodystrophies and multiple sclerosis, and their replenishment by reprogramming or cell conversion strate...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Weider, Matthias, Wegener, Amélie, Schmitt, Christian, Küspert, Melanie, Hillgärtner, Simone, Bösl, Michael R., Hermans-Borgmeyer, Irm, Nait-Oumesmar, Brahim, Wegner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334169/
https://ncbi.nlm.nih.gov/pubmed/25680202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005008
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