SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres

SLX4 interacts with several endonucleases to resolve structural barriers in DNA metabolism. SLX4 also interacts with telomeric protein TRF2 in human cells. The molecular mechanism of these interactions at telomeres remains unknown. Here, we report the crystal structure of the TRF2-binding motif of S...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Wan, Bingbing, Yin, Jinhu, Horvath, Kent, Sarkar, Jaya, Chen, Yong, Wu, Jian, Wan, Ke, Lu, Jian, Gu, Peili, Yu, Eun Young, Lue, Neal F., Chang, Sandy, Liu, Yie, Lei, Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334113/
https://ncbi.nlm.nih.gov/pubmed/24012755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.08.017
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