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PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates.

A target length limitation to PCR amplification of DNA has been identified and addressed. Concomitantly, the base-pair fidelity, the ability to use PCR products as primers, and the maximum yield of target fragment were increased. These improvements were achieved by the combination of a high level of...

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Detalhes bibliográficos
Autor principal: Barnes, W M
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43341/
https://ncbi.nlm.nih.gov/pubmed/8134376
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