Medulloblastoma subgroups remain stable across primary and metastatic compartments

Medulloblastoma comprises four distinct molecular variants with distinct genetics, transcriptomes, and outcomes. Subgroup affiliation has been previously shown to remain stable at the time of recurrence, which likely reflects their distinct cells of origin. However, a therapeutically relevant questi...

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Bibliografske podrobnosti
izdano v:Acta Neuropathol
Main Authors: Wang, Xin, Dubuc, Adrian M., Ramaswamy, Vijay, Mack, Stephen, Gendoo, Deena M.A., Remke, Marc, Wu, Xiaochong, Garzia, Livia, Luu, Betty, Cavalli, Florence, Peacock, John, López, Borja, Skowron, Patryk, Zagzag, David, Lyden, David, Hoffman, Caitlin, Cho, Yoon-Jae, Eberhart, Charles, MacDonald, Tobey, Li, Xiao-Nan, Van Meter, Timothy, Northcott, Paul A., Haibe-Kains, Benjamin, Hawkins, Cynthia, Rutka, James T., Bouffet, Eric, Pfister, Stefan M., Korshunov, Andrey, Taylor, Michael D.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333718/
https://ncbi.nlm.nih.gov/pubmed/25689980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1389-0
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