Medulloblastoma subgroups remain stable across primary and metastatic compartments

Medulloblastoma comprises four distinct molecular variants with distinct genetics, transcriptomes, and outcomes. Subgroup affiliation has been previously shown to remain stable at the time of recurrence, which likely reflects their distinct cells of origin. However, a therapeutically relevant questi...

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Publicat a:Acta Neuropathol
Autors principals: Wang, Xin, Dubuc, Adrian M., Ramaswamy, Vijay, Mack, Stephen, Gendoo, Deena M.A., Remke, Marc, Wu, Xiaochong, Garzia, Livia, Luu, Betty, Cavalli, Florence, Peacock, John, López, Borja, Skowron, Patryk, Zagzag, David, Lyden, David, Hoffman, Caitlin, Cho, Yoon-Jae, Eberhart, Charles, MacDonald, Tobey, Li, Xiao-Nan, Van Meter, Timothy, Northcott, Paul A., Haibe-Kains, Benjamin, Hawkins, Cynthia, Rutka, James T., Bouffet, Eric, Pfister, Stefan M., Korshunov, Andrey, Taylor, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333718/
https://ncbi.nlm.nih.gov/pubmed/25689980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1389-0
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