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Medulloblastoma subgroups remain stable across primary and metastatic compartments

Medulloblastoma comprises four distinct molecular variants with distinct genetics, transcriptomes, and outcomes. Subgroup affiliation has been previously shown to remain stable at the time of recurrence, which likely reflects their distinct cells of origin. However, a therapeutically relevant questi...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Wang, Xin, Dubuc, Adrian M., Ramaswamy, Vijay, Mack, Stephen, Gendoo, Deena M.A., Remke, Marc, Wu, Xiaochong, Garzia, Livia, Luu, Betty, Cavalli, Florence, Peacock, John, López, Borja, Skowron, Patryk, Zagzag, David, Lyden, David, Hoffman, Caitlin, Cho, Yoon-Jae, Eberhart, Charles, MacDonald, Tobey, Li, Xiao-Nan, Van Meter, Timothy, Northcott, Paul A., Haibe-Kains, Benjamin, Hawkins, Cynthia, Rutka, James T., Bouffet, Eric, Pfister, Stefan M., Korshunov, Andrey, Taylor, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333718/
https://ncbi.nlm.nih.gov/pubmed/25689980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1389-0
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