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FLT3 tyrosine kinase inhibitors in acute myeloid leukemia: clinical implications and limitations
Internal tandem duplications of the FMS-like tyrosine kinase 3 (FLT3) gene are one of the most frequent gene mutations in acute myeloid leukemia (AML) and are associated with poor clinical outcome. The remission rate is high with intensive chemotherapy, but most patients eventually relapse. During t...
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| Published in: | Leuk Lymphoma |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333682/ https://ncbi.nlm.nih.gov/pubmed/23631653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2013.800198 |
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