The polymeric mucin Muc5ac is required for allergic airway hyperreactivity

In asthma, airflow obstruction is thought to result primarily from inflammation-triggered airway smooth muscle (ASM) contraction. However, anti-inflammatory and smooth muscle-relaxing treatments are often temporary or ineffective. Overproduction of the mucin MUC5AC is an additional disease feature t...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Evans, Christopher M., Raclawska, Dorota S., Ttofali, Fani, Liptzin, Deborah R., Fletcher, Ashley A., Harper, Daniel N., McGing, Maggie A., McElwee, Melissa M., Williams, Olatunji W., Sanchez, Elizabeth, Roy, Michelle G., Kindrachuk, Kristen N., Wynn, Thomas A., Eltzschig, Holger K., Blackburn, Michael R., Tuvim, Michael J., Janssen, William J., Schwartz, David A., Dickey, Burton F.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333679/
https://ncbi.nlm.nih.gov/pubmed/25687754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7281
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares