The polymeric mucin Muc5ac is required for allergic airway hyperreactivity

In asthma, airflow obstruction is thought to result primarily from inflammation-triggered airway smooth muscle (ASM) contraction. However, anti-inflammatory and smooth muscle-relaxing treatments are often temporary or ineffective. Overproduction of the mucin MUC5AC is an additional disease feature t...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Evans, Christopher M., Raclawska, Dorota S., Ttofali, Fani, Liptzin, Deborah R., Fletcher, Ashley A., Harper, Daniel N., McGing, Maggie A., McElwee, Melissa M., Williams, Olatunji W., Sanchez, Elizabeth, Roy, Michelle G., Kindrachuk, Kristen N., Wynn, Thomas A., Eltzschig, Holger K., Blackburn, Michael R., Tuvim, Michael J., Janssen, William J., Schwartz, David A., Dickey, Burton F.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333679/
https://ncbi.nlm.nih.gov/pubmed/25687754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7281
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