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Markov State Models Provide Insights into Dynamic Modulation of Protein Function

[Image: see text] Protein function is inextricably linked to protein dynamics. As we move from a static structural picture to a dynamic ensemble view of protein structure and function, novel computational paradigms are required for observing and understanding conformational dynamics of proteins and...

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Publicat a:Acc Chem Res
Autors principals: Shukla, Diwakar, Hernández, Carlos X., Weber, Jeffrey K., Pande, Vijay S.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2015
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333613/
https://ncbi.nlm.nih.gov/pubmed/25625937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar5002999
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