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Redox-Neutral α-Oxygenation of Amines: Reaction Development and Elucidation of the Mechanism
[Image: see text] Cyclic secondary amines and 2-hydroxybenzaldehydes or related ketones react to furnish benzo[e][1,3]oxazine structures in generally good yields. This overall redox-neutral amine α-C–H functionalization features a combined reductive N-alkylation/oxidative α-functionalization and is...
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Publicado no: | J Am Chem Soc |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Chemical
Society
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333595/ https://ncbi.nlm.nih.gov/pubmed/24689802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja501988b |
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