Role of the Nuclease of Nontypeable Haemophilus influenzae in Dispersal of Organisms from Biofilms

Nontypeable Haemophilus influenzae (NTHI) forms biofilms in the middle ear during human infection. The biofilm matrix of NTHI contains extracellular DNA. We show that NTHI possesses a potent nuclease, which is a homolog of the thermonuclease of Staphylococcus aureus. Using a biofilm dispersal assay,...

詳細記述

保存先:
書誌詳細
出版年:Infect Immun
主要な著者: Cho, Christine, Chande, Aroon, Gakhar, Lokesh, Bakaletz, Lauren O., Jurcisek, Joseph A., Ketterer, Margaret, Shao, Jian, Gotoh, Kenji, Foster, Eric, Hunt, Jason, O'Brien, Erin, Apicella, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
Molecular Pathogenesis
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333478/
https://ncbi.nlm.nih.gov/pubmed/25547799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02601-14
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