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Switching between polymerase and exonuclease sites in DNA polymerase ε
The balance between exonuclease and polymerase activities promotes DNA synthesis over degradation when nucleotides are correctly added to the new strand by replicative B-family polymerases. Misincorporations shift the balance toward the exonuclease site, and the balance tips back in favor of DNA syn...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333401/ https://ncbi.nlm.nih.gov/pubmed/25550436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1353 |
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