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Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2
Adenosine deaminases acting on RNA (ADARs) hydrolytically deaminate adenosines (A) in a wide variety of duplex RNAs and misregulation of editing is correlated with human disease. However, our understanding of reaction selectivity is limited. ADARs are modular enzymes with multiple double-stranded RN...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333395/ https://ncbi.nlm.nih.gov/pubmed/25564529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1345 |
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