Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing

When messenger RNA splicing occurs co-transcriptionally, the potential for kinetic control based on transcription dynamics is widely recognized. Indeed, perturbation studies have reported that when transcription kinetics are perturbed genetically or pharmacologically splice patterns may change. Howe...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Davis-Turak, Jeremy C., Allison, Karmel, Shokhirev, Maxim N., Ponomarenko, Petr, Tsimring, Lev S., Glass, Christopher K., Johnson, Tracy L., Hoffmann, Alexander
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Computational Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333389/
https://ncbi.nlm.nih.gov/pubmed/25541195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1338
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