Llwytho...
Molecular crowding overcomes the destabilizing effects of mutations in a bacterial ribozyme
The native structure of the Azoarcus group I ribozyme is stabilized by the cooperative formation of tertiary interactions between double helical domains. Thus, even single mutations that break this network of tertiary interactions reduce ribozyme activity in physiological Mg(2+) concentrations. Here...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nucleic Acids Res |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2015
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333387/ https://ncbi.nlm.nih.gov/pubmed/25541198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1335 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|