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Entropic stabilization of folded RNA in crowded solutions measured by SAXS
Non-coding RNAs must fold into specific structures that are stabilized by metal ions and other co-solutes in the cell's interior. Large crowder molecules such as PEG stabilize a bacterial group I ribozyme so that the RNA folds in low Mg(2+) concentrations typical of the cell's interior. To...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5100557/ https://ncbi.nlm.nih.gov/pubmed/27378777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw597 |
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