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Entropic stabilization of folded RNA in crowded solutions measured by SAXS

Non-coding RNAs must fold into specific structures that are stabilized by metal ions and other co-solutes in the cell's interior. Large crowder molecules such as PEG stabilize a bacterial group I ribozyme so that the RNA folds in low Mg(2+) concentrations typical of the cell's interior. To...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Kilburn, Duncan, Behrouzi, Reza, Lee, Hui-Ting, Sarkar, Krishnarjun, Briber, Robert M., Woodson, Sarah A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100557/
https://ncbi.nlm.nih.gov/pubmed/27378777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw597
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