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New insights into the QuikChange(TM) process guide the use of Phusion DNA polymerase for site-directed mutagenesis

The QuikChange(TM) site-directed mutagenesis method is popular but imperfect. An improvement by using partially overlapping primers has been reported several times; however, it is incompatible with the proposed mechanism. The QuikChange(TM) method using complementary primers is proposed to linearly...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Xia, Yongzhen, Chu, Wenqiao, Qi, Qingsheng, Xun, Luying
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333370/
https://ncbi.nlm.nih.gov/pubmed/25399421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1189
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