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Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects

Androgen receptor (AR) signaling is a critical pathway for prostate cancer cells, and androgen-deprivation therapy (ADT) remains the principal treatment for patients with locally advanced and metastatic disease. However, over time, most tumors become resistant to ADT. The view of castration-resistan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Ferraldeschi, R, Welti, J, Luo, J, Attard, G, de Bono, JS
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333106/
https://ncbi.nlm.nih.gov/pubmed/24837363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.115
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