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Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects
Androgen receptor (AR) signaling is a critical pathway for prostate cancer cells, and androgen-deprivation therapy (ADT) remains the principal treatment for patients with locally advanced and metastatic disease. However, over time, most tumors become resistant to ADT. The view of castration-resistan...
Gespeichert in:
Veröffentlicht in: | Oncogene |
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Hauptverfasser: | , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333106/ https://ncbi.nlm.nih.gov/pubmed/24837363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.115 |
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