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Uncoupling Lipid Metabolism from Inflammation through Fatty Acid Binding Protein-Dependent Expression of UCP2

Chronic inflammation in obese adipose tissue is linked to endoplasmic reticulum (ER) stress and systemic insulin resistance. Targeted deletion of the murine fatty acid binding protein (FABP4/aP2) uncouples obesity from inflammation although the mechanism underlying this finding has remained enigmati...

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Publicado en:Mol Cell Biol
Main Authors: Xu, Hongliang, Hertzel, Ann V., Steen, Kaylee A., Wang, Qigui, Suttles, Jill, Bernlohr, David A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333098/
https://ncbi.nlm.nih.gov/pubmed/25582199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01122-14
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