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Identification of a Fatty Acid Binding Protein4-UCP2 Axis Regulating Microglial Mediated Neuroinflammation

Hypothalamic inflammation contributes to metabolic dysregulation and the onset of obesity. Dietary saturated fats activate microglia via a nuclear factor-kappa B (NFκB) mediated pathway to release pro-inflammatory cytokines resulting in dysfunction or death of surrounding neurons. Fatty acid binding...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Neurosci
Hoofdauteurs: Duffy, Cayla M., Xu, Hongliang, Nixon, Joshua P., Bernlohr, David A., Butterick, Tammy A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399884/
https://ncbi.nlm.nih.gov/pubmed/28214555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2017.02.004
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