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FABP4/aP2 Regulates Macrophage Redox Signaling and Inflammasome Activation via Control of UCP2

Obesity-linked metabolic disease is mechanistically associated with the accumulation of proinflammatory macrophages in adipose tissue, leading to increased reactive oxygen species (ROS) production and chronic low-grade inflammation. Previous work has demonstrated that deletion of the adipocyte fatty...

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Publicat a:Mol Cell Biol
Autors principals: Steen, Kaylee A., Xu, Hongliang, Bernlohr, David A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214853/
https://ncbi.nlm.nih.gov/pubmed/27795298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00282-16
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