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FABP4/aP2 Regulates Macrophage Redox Signaling and Inflammasome Activation via Control of UCP2
Obesity-linked metabolic disease is mechanistically associated with the accumulation of proinflammatory macrophages in adipose tissue, leading to increased reactive oxygen species (ROS) production and chronic low-grade inflammation. Previous work has demonstrated that deletion of the adipocyte fatty...
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| Udgivet i: | Mol Cell Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5214853/ https://ncbi.nlm.nih.gov/pubmed/27795298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00282-16 |
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