Connexin 43 Channels are Essential for Normal Bone Structure and Osteocyte Viability

Connexin (Cx) 43 serves important roles in bone function and development. Targeted deletion of Cx43 in osteoblasts or osteocytes leads to increased osteocyte apoptosis, osteoclast recruitment, and reduced biomechanical properties. Cx43 forms both gap junction channels and hemichannels, which mediate...

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Publicado en:J Bone Miner Res
Autores principales: Xu, Huiyun, Gu, Sumin, Riquelme, Manuel A., Burra, Sirisha, Callaway, Danielle, Cheng, Hongyun, Guda, Teja, Schmitz, James, Fajardo, Roberto J., Werner, Sherry L., Zhao, Hong, Shang, Peng, Johnson, Mark L., Bonewald, Lynda F., Jiang, Jean X.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333056/
https://ncbi.nlm.nih.gov/pubmed/25270829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2374
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