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Connexin 43 Channels are Essential for Normal Bone Structure and Osteocyte Viability

Connexin (Cx) 43 serves important roles in bone function and development. Targeted deletion of Cx43 in osteoblasts or osteocytes leads to increased osteocyte apoptosis, osteoclast recruitment, and reduced biomechanical properties. Cx43 forms both gap junction channels and hemichannels, which mediate...

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Detaylı Bibliyografya
Yayımlandı:J Bone Miner Res
Asıl Yazarlar: Xu, Huiyun, Gu, Sumin, Riquelme, Manuel A., Burra, Sirisha, Callaway, Danielle, Cheng, Hongyun, Guda, Teja, Schmitz, James, Fajardo, Roberto J., Werner, Sherry L., Zhao, Hong, Shang, Peng, Johnson, Mark L., Bonewald, Lynda F., Jiang, Jean X.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333056/
https://ncbi.nlm.nih.gov/pubmed/25270829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2374
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