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Connexin 43 Channels are Essential for Normal Bone Structure and Osteocyte Viability
Connexin (Cx) 43 serves important roles in bone function and development. Targeted deletion of Cx43 in osteoblasts or osteocytes leads to increased osteocyte apoptosis, osteoclast recruitment, and reduced biomechanical properties. Cx43 forms both gap junction channels and hemichannels, which mediate...
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| Yayımlandı: | J Bone Miner Res |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333056/ https://ncbi.nlm.nih.gov/pubmed/25270829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2374 |
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