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Affinity purification–mass spectrometry and network analysis to understand protein-protein interactions

By determining protein-protein interactions in normal, diseased and infected cells, we can improve our understanding of cellular systems and their reaction to various perturbations. In this protocol, we discuss how to use data obtained in affinity purification–mass spectrometry (AP-MS) experiments t...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Protoc
Auteurs principaux: Morris, John H, Knudsen, Giselle M, Verschueren, Erik, Johnson, Jeffrey R, Cimermancic, Peter, Greninger, Alexander L, Pico, Alexander R
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332878/
https://ncbi.nlm.nih.gov/pubmed/25275790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.164
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