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Affinity purification–mass spectrometry and network analysis to understand protein-protein interactions

By determining protein-protein interactions in normal, diseased and infected cells, we can improve our understanding of cellular systems and their reaction to various perturbations. In this protocol, we discuss how to use data obtained in affinity purification–mass spectrometry (AP-MS) experiments t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Protoc
Main Authors: Morris, John H, Knudsen, Giselle M, Verschueren, Erik, Johnson, Jeffrey R, Cimermancic, Peter, Greninger, Alexander L, Pico, Alexander R
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332878/
https://ncbi.nlm.nih.gov/pubmed/25275790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.164
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