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Predicting direct protein interactions from affinity purification mass spectrometry data
BACKGROUND: Affinity purification followed by mass spectrometry identification (AP-MS) is an increasingly popular approach to observe protein-protein interactions (PPI) in vivo. One drawback of AP-MS, however, is that it is prone to detecting indirect interactions mixed with direct physical interact...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991326/ https://ncbi.nlm.nih.gov/pubmed/21034440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-5-34 |
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