MJ-66 induces malignant glioma cells G2/M phase arrest and mitotic catastrophe through regulation of cyclin B1/Cdk1 complex

Malignant gliomas are among the most devastating cancers as they are resistant to many kinds of treatment. Despite recent advances in the diagnosis and treatment, the prognosis of patients remains very poor and the development of new drug is urgently needed. Here, we report that a synthetic quinazol...

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Pubblicato in:Neuropharmacology
Autori principali: Liu, Wei-Ting, Chen, Ching, Lu, I-Chen, Kuo, Sheng-Chu, Lee, Kuo-Hsiung, Chen, Tai-Lin, Song, Ta-Shu, Lu, Yi-Liang, Gean, Po-Wu, Hour, Mann-Jen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332812/
https://ncbi.nlm.nih.gov/pubmed/25107587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.07.014
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