Sorafenib Ameliorates Renal Fibrosis through Inhibition of TGF-β-Induced Epithelial-Mesenchymal Transition

OBJECTIVE: This study was to investigate whether sorafenib can inhibit the progression of renal fibrosis and to study the possible mechanisms of this effect. METHODS: Eight-week-old rats were subjected to unilateral ureteral obstruction (UUO) and were intragastrically administered sorafenib, while c...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Jia, Lining, Ma, Xiaotao, Gui, Baosong, Ge, Heng, Wang, Li, Ou, Yan, Tian, Lifang, Chen, Zhao, Duan, Zhaoyang, Han, Jin, Fu, Rongguo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332653/
https://ncbi.nlm.nih.gov/pubmed/25679376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117757
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker