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Progress in Elucidating the Structural and Dynamic Character of G Protein-Coupled Receptor Oligomers for Use in Drug Discovery

G Protein-Coupled Receptors (GPCRs) are the most targeted group of proteins for the development of therapeutic drugs. Until the last decade, structural information about this family of membrane proteins was relatively scarce, and their mechanisms of ligand binding and signal transduction were modele...

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Detalles Bibliográficos
Publicado en:Curr Pharm Des
Main Authors: Bortolato, A., Mobarec, J.C., Provasi, D., Filizola, M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332530/
https://ncbi.nlm.nih.gov/pubmed/20028319
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