LSD1 Overexpression Is Associated with Poor Prognosis in Basal-Like Breast Cancer, and Sensitivity to PARP Inhibition

LSD1, a lysine-specific histone demethylase, is overexpressed in several types of cancers and linked to poor outcomes. In breast cancer, the significance of LSD1 overexpression is not clear. We have performed an in silico analysis to assess the relationship of LSD1 expression to clinical outcome. We...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Nagasawa, Satoi, Sedukhina, Anna S., Nakagawa, Yuko, Maeda, Ichiro, Kubota, Manabu, Ohnuma, Shigeko, Tsugawa, Koichiro, Ohta, Tomohiko, Roche-Molina, Marta, Bernal, Juan A., Narváez, Ana J., Jeyasekharan, Anand D., Sato, Ko
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332491/
https://ncbi.nlm.nih.gov/pubmed/25679396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118002
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items