Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer

The agonistic/antagonistic biocharacter of selective estrogen receptor modulators (SERMs) can have therapeutic advantages, particularly in the case of premenopausal breast cancers. Although the contradictory effects of these modulators have been studied in terms of crosstalk between the estrogen rec...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Johmura, Yoshikazu, Maeda, Ichiro, Suzuki, Narumi, Wu, Wenwen, Goda, Atsushi, Morita, Mariko, Yamaguchi, Kiyoshi, Yamamoto, Mizuki, Nagasawa, Satoi, Kojima, Yasuyuki, Tsugawa, Koichiro, Inoue, Natsuko, Miyoshi, Yasuo, Osako, Tomo, Akiyama, Futoshi, Maruyama, Reo, Inoue, Jun-ichiro, Furukawa, Yoichi, Ohta, Tomohiko, Nakanishi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264734/
https://ncbi.nlm.nih.gov/pubmed/30418174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121679
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