Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer

The agonistic/antagonistic biocharacter of selective estrogen receptor modulators (SERMs) can have therapeutic advantages, particularly in the case of premenopausal breast cancers. Although the contradictory effects of these modulators have been studied in terms of crosstalk between the estrogen rec...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Johmura, Yoshikazu, Maeda, Ichiro, Suzuki, Narumi, Wu, Wenwen, Goda, Atsushi, Morita, Mariko, Yamaguchi, Kiyoshi, Yamamoto, Mizuki, Nagasawa, Satoi, Kojima, Yasuyuki, Tsugawa, Koichiro, Inoue, Natsuko, Miyoshi, Yasuo, Osako, Tomo, Akiyama, Futoshi, Maruyama, Reo, Inoue, Jun-ichiro, Furukawa, Yoichi, Ohta, Tomohiko, Nakanishi, Makoto
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2018
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264734/
https://ncbi.nlm.nih.gov/pubmed/30418174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121679
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