Functional and dysfunctional conformers of human neuroserpin characterized by optical spectroscopies and Molecular Dynamics

Neuroserpin (NS) is a serine protease inhibitor (SERPIN) involved in different neurological pathologies, including the Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB), related to the aberrant polymerization of NS mutants. Here we present an in vitro and in silico characterization o...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Biochim Biophys Acta
Hlavní autoři: Noto, Rosina, Santangelo, Maria Grazia, Levantino, Matteo, Cupane, Antonio, Mangione, Maria Rosalia, Parisi, Daniele, Ricagno, Stefano, Bolognesi, Martino, Manno, Mauro, Martorana, Vincenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Pub. Co 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332418/
https://ncbi.nlm.nih.gov/pubmed/25450507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2014.10.002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky