Altering the redox state of skeletal muscle by glutathione depletion increases the exercise‐activation of PGC‐1α

We investigated the relationship between markers of mitochondrial biogenesis, cell signaling, and antioxidant enzymes by depleting skeletal muscle glutathione with diethyl maleate (DEM) which resulted in a demonstrable increase in oxidative stress during exercise. Animals were divided into six group...

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Foilsithe in:Physiol Rep
Main Authors: Strobel, Natalie A., Matsumoto, Aya, Peake, Jonathan M., Marsh, Susan A., Peternelj, Tina‐Tinkara, Briskey, David, Fassett, Robert G., Coombes, Jeff S., Wadley, Glenn D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Wiley Periodicals, Inc. 2014
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332207/
https://ncbi.nlm.nih.gov/pubmed/25538148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12224
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