Altering the redox state of skeletal muscle by glutathione depletion increases the exercise‐activation of PGC‐1α

We investigated the relationship between markers of mitochondrial biogenesis, cell signaling, and antioxidant enzymes by depleting skeletal muscle glutathione with diethyl maleate (DEM) which resulted in a demonstrable increase in oxidative stress during exercise. Animals were divided into six group...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Strobel, Natalie A., Matsumoto, Aya, Peake, Jonathan M., Marsh, Susan A., Peternelj, Tina‐Tinkara, Briskey, David, Fassett, Robert G., Coombes, Jeff S., Wadley, Glenn D.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332207/
https://ncbi.nlm.nih.gov/pubmed/25538148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12224
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